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This page has been updated. This page will automatically redirect to the new site or click the link below to go there now: http://www.bellaireneurology.com/seizure/epil_trt_tiagabine.html
Tiagabine® or Gabitril is one of the newer antiepileptics with which
I personally have very little experience. It is available in tablet form
in multiple dosages.
The medication is felt to work by increasing GABA, an inhibitory neurotransmitter,
levels. It does not cause any major side effects affecting liver, bone
marrow, etc. It does have some limited drug interactions with some of
the other antiepileptic medications but does not generally affect other
medications. Its most common dose limiting side effect is sedation.
In epilepsy, the medication is indicated in partial onset seizures.
There have been rare reports of it causing problems in patients with generalized
seizures.
I have not reviewed or used it sufficiently in epilepsy or other areas
to comment further at this time.
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